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Rheumatoid Arthritis Causes, Risk Factors & Research

Do you know rheumatoid arthritis causes and it’s risk factors? People usually don’t know what are the reasons behind it. Today we have asked Dr. Vijay Rao who is a Consultant in the Rheumatology Department of
Medical hospital, Bangalow.  Rheumatoid arthritis is genetically mediated. Hence, the gene defect causes this.

Rheumatoid Arthritis Causes and Risk Factors

Most of the patients ask does that mean it’s hereditary because none of my family members had it. The answer is no. Genetically mediated means the gene is altered in the patient’s body causing something called as mutation and hence the function of the gene is altered. This altered functional gene produces certain chemicals in the body called antibodies which destroys the joint.

Rheumatoid Arthritis Causes

So this is an autoimmune disease where the body’s own immune system attacks the joints and other parts of the body destroying it. Hence it called self-directed immunity or autoimmunity. Genetically prone people is already on the list.

Is it Genetic Heritage?

The answer is it’s not hereditary but if you have family members having rheumatoid arthritis then you are definitely a slightly more risk.


If one does smoking than smoking causes a chemical in the body chemical process in the body. This happens in the lungs which produces antibodies called auntie CCP antibodies which are basically like ballistic missiles. They behave attacking the joints and internal organs.

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So smoking, genetic abnormalities, strong family history, and sedentary lifestyle is certainly associated with rheumatoid arthritis causes. However, Rheumatoid Arthritis Congestive Heart failure may occur too. Therefore, all these factors play the role.  Another important thing is obesity so being lean and physically active certainly gives you a lesser chance of developing.

Via-  Dr. Vijay Rao (Consultant)
Rheumatology Department
Medical hospital, Bangalow




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