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Tizanidine High Side Effects, Uses and Abuse

Today we answer questions like, What is tizanidine high? What is it used for? What side effects does it have? Here are some of the basic Questions and Answers regarding it.

Tizanidine High

It is a prescription muscle relaxant for reducing certain fibromyalgia pain types and muscle tension. It is rarely prescribed for medicinal purposes but it is frequently abused and is scheduled as a controlled substance in some states.

Addiction and Abuse

Tizanidine high can be fatal in overdose. It is potential for causing addiction is well-known. Hence, people can become addicted to it and similar drugs even when these drugs are the prescribed treatment. However, others deliberately use this medication to enhance the effects of tizanidine and alcohol or other drugs.

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Is Tizanidine Addictive?

It acts directly on the central nervous system rather than the skeletal muscles. It seems to interrupt communication between certain areas of the brain and the spinal cord which results in sedation and altered perception of pain. Therefore, individuals abuse this medication by taking more than the prescribed amount in order to enhance the sedating effects.

Tizanidine high

Tizanidine Side Effects

What are the side effects? The side effects include:

  • Agitation
  • Depression
  • Dizziness
  • Drowsiness
  • Facial flushing
  • Fainting
  • Headache
  • Insomnia
  • Shaking
  • Tremors

Mode of Administration & Contraindications:

Oral use. Take the tablets with a glass of water. However, the contraindication includes, Hypersensitivity, concomitant administration with fluvoxamine or ciprofloxacin. Furthermore, the withdrawal symptoms of Tizanidine high include abdominal cramps, headache, insomnia, and nausea.

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Warnings and Precautions:

Liver failure (impaired liver function), elderly. Hypotension (loss of consciousness and circulatory collapse) may occur. Therefore, do not interrupt abruptly (rebound hypertension and tachycardia). Periodic hepatic control. However, Risk of sedation (50%) and hallucinations (3%). Therefore, not recommended for children. Hence, avoid concomitant use with other CYP1A2 inhibitors.

Fibromyalgia and Pregnancy

Pregnancy and Breastfeeding:

No clinical data are available in humans. It should not be used unless the benefit clearly outweighs the risks. It is not known whether tizanidine is excreted by milk in humans, although it is known that in animals it passes into milk in small amounts. Hence, it is not recommended during fibromyalgia pregnancy and breastfeeding.



This content is strictly an overview and is for informational and educational purposes only. Neither the sources of this content nor the publisher of this content takes responsibility. All readers of this content, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any medication.


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This Post Has One Comment

  1. stewart

    the side affects are worse than the pain your dealing with making it scarier to take it
    how can patients take it without being worried about the side effects

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